Project Leaders – Hasanuddin University Medical Research Center

Agussalim Bukhari, MD. PhD.

Diabetes Mellitus and Metabolic Syndrome Project Leader

Senior Lecturer in Clinical Nutrition and Metabolism

Biography

Graduated as Medical Doctor from Medical Faculty Hasanuddin University in 1996. He used to work in rural area Primary Health Centre for three years (1996-1999). He started his career as a lecturer at Medical Faculty Hasanuddin University in 1999. After obtaining his master degree in Clinical Nutrition from Monash University Australia in 2002, He continued to study at The Department of Internal Medicne, University of Toyama Japan for his Doctoral degree in Diabetes Mellitus and Metabolic Syndrome and completed it in 2008.

After returning back to Indonesia he joined Medical Faculty Research Unit (currently known as (HUMRC) and has been engaged in research on metabolic syndrome and nutrigenomics. He also involved in improving the animal laboratory of the Medical Faculty to International standard in housing system. He assisted the laboratory technician for capacity building in ELISA analysis and Real Time RT PCR method for detecting polymorphisms as a new alternative of RFLP method.

Research interest

Agussalim Bukhari has research of interest in Obesity-induced insulin resistance, Nutrigenomics, and Clinical Nutrition & metabolisms. He is also interested in immune system-related studies.

Peer-Reviewed Publications

He J, Usui I, Ishizuka K, Kanatani Y, Iwata M, Hirata K, Bukhari A, Haruta T, Sasaoka T, Kobayashi M, Interlekuin 1-Alpha inhibits insulin signaling via phosphorylating insulin receptor substrate-1 on serine residues in 3T3-L1 adipoctes , Mol Endocrinol 20:114-124, 2006

Kanatani H, Usui I, Ishizuka, Bukhari A, Fujisaka, Urakaze M, Haruta T, Kishimoto T, Naka T, Kobayashi M. Effects of Pioglitazone on suppressor of cytokine signaling-3. Potential mechanisms of its effects on insulin sensitivity and adiponectin expression. Diabetes 56:795–803, 2007

Ishizuka K, Usui I, Kanatani Y, Bukhari A, He J, Fujisaka S, Yamazaki Y, Suzuki H, Hiratani K, Ishiki M, Iwata M, Urakaze M, Haruta T, Kobayashi M. Chronic Tumor Necrosis Factor-alpha Treatment Causes Insulin Resistance via Insulin Receptor Substrate-1 Serine Phosphorylation and Suppressor of Cytokine Signaling-3 Induction in 3T3-L1 Adipocytes Endocrinol. 148:2994–3003, 2007

Uno T, He J, Usui I, Kanatani Y, Bukhari A, Fujisaka S, Yamazaki Y, Suzuki H, Iwata M, Ishiki M, Urakaze M, Haruta T, Ogawa H, Kobayashi M. Long-term interleukin-1alpha treatment inhibits insulin signaling via IL-6 production and SOCS3 expression in 3T3-L1 adipocytes. Horm Metab Res. 2008 Jan;40(1):8-12. Epub 2007 Dec 17.

Gomi T, Takusagawa F, Nishizawa M, Agussalim B, Usui I, Sugiyama E, Taki H, Shinoda K, Hounoki H, Miwa T, Tobe K, Kobayashi M, Ishimoto T, Ogawa H, Mori H. Cloning, bacterial expression, and unique structure of adenosylhomocysteine hydrolase-like protein 1, or inositol 1,4,5-triphosphate receptor-binding protein from mouse kidney. Biochim Biophys Acta. 2008 Nov;1784(11):1786-94.

Yamazaki Y, Usui I, Kanatani Y, Matsuya Y, Tsuneyama K, Fujisaka S, Bukhari A, Suzuki H, Senda S, Imanishi S, Hirata K, Ishiki M, Hayashi R, Urakaze M, Nemoto H, Kobayashi M, Tobe K. Treatment with SRT1720, a SIRT1 Activator, Ameliorates Fatty Liver with Reduced Expression of Lipogenic Enzymes in MSG Mice. Am J Physiol Endocrinol Metab. 2009 Sep 1

Fujisaka S, Usui I, Bukhari A, Ikutani M, Oya T, Kanatani Y, Tsuneyama K, Nagai Y, Takatsu K, Urakaze M, Kobayashi M, Tobe K. Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice. Diabetes. 2009 Nov;58(11):2574-82

Asamizu S, Urakaze M, Kobashi C, Ishiki M, Norel Din AK, Fujisaka S, Kanatani Y, Bukahari A, Senda S, Suzuki H, Yamazaki Y, Iwata M, Usui I, Yamazaki K, Ogawa H, Kobayashi M, Tobe K. Angiotensin II enhances the increase in monocyte chemoattractant protein-1 production induced by tumor necrosis factor-{alpha} from 3T3-L1 preadipocytes. J Endocrinol. 2009 Aug;202(2):199-205.

Bukhari A, Usui I, Kanatani Y, Fujisaka S Yamazaki Y, Suzuki H, Senda S, Ishiki M, Urakaze M, Kobayashi M, Tobe K. Interleukin-10 improves glucose metabolism by Increasing Expression of Genes Involved in Beta-oxidation and Mitochondrial Oxphos in The Skeletal muscles. J Nutrigenetics and Nutrigenomics, Vol 3 No 2-3, 2010

Bukhari A, As’ad S, Astuti N, et al. Combination of Fish Oil and Curcumin Ameliorate Insulin Resistance by Increasing Serum Adiponectin and Expression of Fat Oxidation Marker PPAR alpha and Decreasing Serum and Expression of TNF-alpha in Obese Subjects and Diet-Induced Obese Mice J Nutrigenet Nutrigenomics 2014;7:1-38

Yusnita Rifai is a Head of Pharmaceutical Chemistry laboratory in Hasanuddin University. She did her master degree at School of Medicine, Flinders University Australia in 2006 under the supervision of Professor Gino Saccone. Then graduated with a PhD in 2011 (Chiba University, Japan), being trained in the laboratory of Professor Masami Ishibashi, Graduate School of Pharmaceutical Sciences. Her research interests focus on three broad areas: Drug Synthesis, Natural Product Chemistry and Biotechnology. She explores unique compounds from either marine or natural resources as anti cancers, anti inflammations and anti osteoporosis. A lot of her work relies on different types of spectroscopy and chromatography instruments. She also makes use wide ranges of synthesis and bioassay systems to further her research. Her works in medicinal chemistry won the Timmerman award in 2013.

In recent works, she has received the 2013 Nasional L’Oreal for Woman in Science fellowship to set up a biosensor diagnostic system for a c-terminal telopeptide detection which determined the earliest stage of bone loss in osteoporosis. This diagnostic system provided better understanding of bone matrix remodeling and of bone markers changing over time. She has also been awarded the 2014 Endeavour postdoctoral fellowship to pursue post-doctoral studies in the laboratory of Dr. Ian Altena and Dr. Chris Scarlett at the University of Newcastle Australia and currently collaborates with University of Calgary-Canada for the novel salivary peptide feG project and University Sains Malaysia for the GLI inhibitor research. Yusnita Rifai is served as an international conference committee of the world academy of science engineering and technology and participates in several publications as a reviewer.

She published 11 peer-reviewed international journals while presenting either a poster or oral presentations in many annual meetings of Pharmaceutical Society related to the research field. She received grants from Flinders Medical Centre Foundation, Australia (2005), Grant-in-Aid JSPS (The Japan Society for the Promotion of Science), Japan (2010-2011), Grant Young A Award from Chiba University (2010), and Grant Insentif Sinas from Indonesian Ministry of Research and Technology (2012-2013), Patent receiver grant for Uber HKI from DIKTI (2013), Grant Drug Discovery from Indonesian Ministry of Health (2014).

maisuri

Dr. Maisuri T. Chalid, MD, SpOG(K).

Tropical Disease in Pregnancy Project Leader

Senior Lecturer in Obstetrics and Gynecology

Biography

Maisuri T. Chalid graduated from Hasanuddin University Medical Faculty in 1993 and finished her duty work at Makkasau health centre, Pusat Kesehatan Masyarakat, Makkassar in 1996. In the same year, she was recruited as a lecturer in Faculty of Medicine, Hasanuddin University. She entered the Postgraduate Program of Specialist in Obstetrics and Gynecology from 1998 to 2002.

After finished her study, she worked as a clinician at Wahidin Sudirohusodo Hospital, and began her carrier as a lecturer in Obstetrics and Gynecology of Hasanuddin University –Makassar.

She conducted several studies in preeclampsia which funded by Risbin Iptekdok –Litbangkes- Ministry of Health, in 1999-2001.

In 2004 she got a scholarship from The International Association for Maternal and Neonatal Health (IAMANEH) to attend the postgraduate course in Reproductive Health Research, at World Health Organization (WHO), Geneva, Switzerland, which counducted by Geneva Foundation for Medical Education and Research (GFMER) and World Health Organization (WHO).

To develop her clinical competence as a professional in Obstetrics Gynecology, she also has studied to be a Consultant in the field of Maternal Fetal Medicine at Padjadjaran University, Bandung and finished in 2007. Then she continued entering the Fellowship Program in Maternal Fetal Medicine at KK Hospital-Singapore, in the same year.

She studied at Doctoral degree of Hasanuddin University Postgraduate Program, and finished her dissertation at 2008 about the role of angiogenic factors on the onset of preeclampsia.

She conducted some research in Maternal Fetal Health, particularly in the term of preeclampsia, preterm birth and infectious diseases in pregnant women. In 2012 she attended the DAAD Summerschool on Mother and Child Health, at University of Goettingen, Goettingen – Germany.

Maisuri has actively involved in teaching Obstetrics and Gynecology for trainees, residents and medical undergraduate students, supervised candidate of master, specialist and doctoral students, from Hasanuddin University and other institutions which affiliated or collaborated with Hasanuddin University. She also contributes as a clinical trainer in continuing professional development program in Emergency Obstetrics and Obstetrics Ultrasound Courses, which conducted clinical training for Obstetricians, doctors, and midwifes in South Sulawesi and eastern part of Indonesia.

Research interest

Research on the topics: preeclampsia, preterm birth.
Research on tropical diseases in pregnancy:
- Seroprevalence and seroconversion of Cytomegalovirus (CMV) in pregnancy (research funding from HPEQ project 2012).
- Vertical transmission of Hepatitis B virus: contribution of viral load, malaria, placenta barrier and modes of delivery (research funding from BOPTN, DIKTI 2013).
- Molecular characterization of DNA Hepatitis B Virus in family with Hepatitis B positive mothers (research funding from BOPTN, DIKTI 2014).
- Helminthiasis in pregnancy, Makassar (2014-2015)
- The effect of helminth infection in pregnancy on serum albumin level and pregnancy outcome (published in Indonesian Journal of Obstetrics and Gynecology, January 2015).
- Maternal ferritin concentration on maternal helminthiasis and its relation to newborn ferritin concentration.

Publications

Oktafandi HO, Dewanti NR, Tanra AH, Patellongi IJ, Chalid MT. Effect of Intrathecal Labor Analgesia (ILA) in Normal Labor Study on the Dynamics of Pain Intensity and Level of Prostaglandin (PGE2) Maternal Plasma. International Journal of Sciences: Basic and Applied Research 2016; 26:3: 88-100.
Fujiko M, Chalid MT, Turyadi, Susan I , Maghfira, Syafri, Wahyuni R, Patellongi I, Massi MN, Muljono DH. Chronic Hepatitis B in Pregnant Women: Is Quantitative HBsAg useful for viral load prediction? International Journal of Infectious Diseases 41 (2015) 83-89.
Chalid MT, Fujiko M, Patellongi IJ, Massi N, Muljono DM, Poster session: The Pattern of Hepatitis B vertical Transmission during Labor: Role of Viral load, Placenta and Modes of Delivery. In: Program & Abstract book of the 11th Asia Pacific Congress in Maternal Fetal Medicine, Taipei 27-29 November 2015.
Wibowo N, Mose JC, Karkata MK, Purwaka BT , Kristanto H, Chalid MT, Yusrawati, Sitepu M, Kaeng JJ, Bernolian N, Pramusinto D, Irwinda R. The status of probiotics supplementation during pregnancy. Med J Indones. 2015;24:120-30.
Ridwan S, Wahyuni S, Chalid MT, Helminth Infection in Pregnancy: Effect on Serum Albumin Level and Pregnancy Outcome. Indonesian Journal Obstetrics and Gynecology January 2015. Vol 3:1; 19-25.
Daido I, Tahir AM, Chalid MT, Changes of Body Mass Index and Lipid Profile in Injectable Depo Medroxyprogesteron Acetate an Levonorgestrel Implant Acceptors. Indonesian Journal of Obstetrics and Gynecology July 2014. Vol 2: 3 :121-125.
Chalid MT. Gambaran umum program 1000 hari awal kehidupan. Dalam: Chalid MT, Wahyuni S, Islam AI, eds. Buku Acuan 1000 Hari Awal Kehidupan. Fk UNHAS Makassar: Sagung Seto; 2014. Hal 7-19.
Chalid MT, Syahruni B. Komunikasi, konseling dan kesantunan budaya lokal. Dalam: Chalid MT, Wahyuni S, Islam AI, eds. Buku Acuan 1000 Hari Awal Kehidupan. Fk UNHAS Makassar: Sagung Seto; 2014. Hal 21-39.
Nurmasida, Lukas E, Irianta T, Chalid SM. Perbandingan kadar serum p38 Mitogen Activated Proetein Kinase (MAPK), trombosit, dan asam urat pada penderita preeclampsia berat dan sindroma HELLP. Indonesian Journal of Obstetrics and Gynecology August 2014. Volume 2: suppl 1: 14
Busra MS, Chalid MT, Malinta U. Seroprevalensi dan faktor risiko penularan sitomegalovirus pada ibu hamil. Indonesian Journal of Obstetrics and Gynecology August 2014. Volume 2: suppl 1: 7.
Chalid MT, Muljono DH. Vertical transmission of Hepatitis B Virus: The role of placental barrier, modes of delivery, viral load and immunoprophylaxis of neonates. In: Uwe Gross and Kerstin Wydra eds. Maternal-Child Health, Interdiciplinary Aspects Within The Perspective of Global Health. Goettingen: Universitat Verlag Goettingen 2013: p. 245-56.
Wantania J, Bakri S, Pandelaki K, Chalid M. Altered level of Soluble fms- like Tyrosine Kinase (sFlt1), Hypoxia Inducible Factor(HIF-1α) in Normotensive pregnancy and Preeclampsia. The Indonesian Biomedical Journal 2013. Vol 5:2: 121-8.
Chalid M, Fujiko M, Maghfira, Turyadi, Khobar KE, Nursanty NKD , Massi MN, Muljono DH. Transmisi vertikal virus hepatitis B dari ibu dengan HBsAg positif di Makassar: Studi pendahuluan. Buku Prosiding. In: Waleleng BJ, Tendean L, Haroen H eds. Buku Abstrak Kongres Nasional PGI-PEGI dan Pekan Ilmiah Nasional XX PPHI. Perkumpulan Gastroenterologi Indonesia dan Perkumpulan Endoskopi Gastrointestinal Indonesia Cabang Sulawesi Utara 2013. ISBN No: 9789792921083. p.270-271.
Arsyad AA, Adam AM, Amiruddin MD, Ilyas F, Massi N, Chalid MT. Comparison of local and systemic interleukin 10 (IL)-10 levels on the pregnant women with bacterial vaginosis. Indonesian Journal of Dermatology and Veneorology 2013. Vol 2: 2: 9-15.
Chalid M, Yusuf I, Patellongi I, Miskad U. The dinamics of angiogenic factors, endothelial and placental dysfunction in maternal plasma and placental expression of early and late onset preeclampsia; possibility of combining the classification diagnosis and the onset of preeclampsia based on angiogenic factors. International Journal of Gynecology & Obstetrics – October 2012 (Vol. 119 Supplement 3, Page S308, DOI: 10.1016/S0020-7292(12)60565-7)
Chalid MT, Azis A. Profil pengetahuan, sikap dan tingkat partisipasi pasangan usia subur terhadap penggunaan kontrasepsi pada masyarakat Muslim pesantren. In: Rambulangi J, Tahir M, Abdullah N, Chalid MT eds. Buku Prosiding 2 Kongres Himpunan Fertilitas Endokrinologi Reproduksi VI. dan Perkumpulan Menopause Indonesia IV. Makassar: Production House FK-UH & Dua satu press 2013. ISBN No:9786029992519: p. 575-580.
Lisangan I, Chalid MT, Lotisna D. A Comparison between the level of Interleukin 10 (IL-10) in term and preterm labor. Indonesian Journal of Obstetrics and Gynecology. Vol 36, No 4, October 2012:163-166
Moningkey S, Yusuf I, Sutrisna B, Chalid MT. The role of dislipidemia in the early and late onset of preeclampsia. Medika, Jurnal Kedokteran Indonesia 2012. Vol 37:10. 752–760.
Wahyu S, Bukhari A, Chalid MT. Relationship trigliserida level, BMI, waist circumference with the degree of premenstrual syndrome in women of reproductive age. Jurnal Sains dan Teknologi Kesehatan April 2012. Vol.2 No.2 : 140 – 146.
Chalid MT, Patellongi I, Yusuf I. Early and late onset of Preeclampsia; Different pathomechanism based on clinical and angiogenesis studies. Jurnal Sains dan Teknologi Kesehatan, Oktober 2011.Vol.1 No.3 : 233 – 242 .
IdrisI, Patellongi I, Agustina, Bahrun U, Chalid MT, Natzir R, Bukhari A. The Level of C-Reactive Protein (hs-CRP) in preeclamptic pregnancy. Jurnal Sains dan Teknologi Kesehatan 2011, Vol 1: 3 : 296 – 300
Idris I, Chalid MT, Riu D, Sinrang W, Patellongi I, Yusuf I. Polymorphisms of T/C 8002 Endothelin-1 gene, Body Mass Index and gestational hypertension. The Indonesian Journal of Physiology 2010. Vol 9:2: 109-113.
Khosal L, Lukas E, Chalid MT., Mansyur A. Analysis of meconium content in amniotic fluid during labour and the level of lactacid acid in the newborn baby (preliminary report). Indonesian Journal of Obstetrics & Gynecology, Vol 33, Suppl 1: 14-15, August 2009.
Gunawan A, Goysal Y, Chalid MT. Kelainan Neurologik pada Kehamilan (Neurologic disorder in pregnancy). In: Ilmu Kedokteran Fetomaternal, 1st ed, Himpunan Kedokteran Fetomaternal. POGI, Surabaya, 2004. p: 606-621.
Chalid MT, Merialdi M. Antioxidants supplementation in prevention of preeclampsia, a review of clinical trials. Geneva Foundation for Medical Education and Research. 2004. Geneva, Switzerland. Available on http://www. gfmer.ch/PGC-RH_2004/
Chalid MT. Substance abuse in pregnancy (a literature review). Nusantara Medical Journal 2002; 23: 3: 699-704.
Chalid MT, Rambulangi J, Patellongi IJ. The dynamics of nitrite oxide, lipid peroxide, superokside dismutase in maternal serum of preeclamptic patients. Nusantara Medical Journal. 2002;23: 2: 607-18

Prof . Muh. Nasrum Massi, MD. PhD.

Biography

After graduated from Hasanuddin University Medical Faculty, Indonesia (1994) Muh. Nasrum Massi worked as physician in Nene Mallomo Hospital in Sidrap district, South Sulawesi. In 1996, he began his carrier as a university lecturer in Faculty of Medicine, Hasanuddin University and was appointed in the Department of Microbiology. Following year until 2000 he jointed with several infectious disease studies in the field of microbiology and infectious disease (Leprosy and Salmonella), In April 2000 he began his doctoral studies at International Centre for medical Research, Kobe University, Japan to study Molecular Diagnostic of Infectious Disease and received his Ph.D in 2005. Since 2008 he was elected as a chairman of Medical Microbiology Department, Faculty of Medicine, UNHAS. Currently Muh. Nasrum Massi working as a TB clinical investigator in NITD-Eijkman -Hasanuddin Clinical Research Initiative (NEHCRI), a unit affiliates to Wahidin Hospital in Makassar, which concentrates in tropical diseases research. Since 2010, he became a Professor in Medical Microbiology department in Hasanuddin University Medical School. In 2014, he was appointed as a vice Dean of student affair Medical Faculty of Hasanuddin University, Makassar, South Sulawesi, Indonesia.

Research interested in studying molecular-epidemiology infectioud diseases, especially in Tuberculosis, Leprosy and Salmonella.

Nasrum was appointed as member of national committee of emerging and re-emerging infectious disease, Department of Health since 2011 and member of consortium of TB Vaccine research activities from Research and development, Department of Health, Indonesia.

Peer-Reviewed Publications

The antituberculosis drug rifampicin is activated by 2’,5’-dimethyl benzopelargonolactone from the leaf of coleus atropurpureus L benth. Int J Pharm Bio Sci 2014 Jan; 5(1): (B) 758 – 764

A genetic variant of glutamate cysteine ligase gene is an oxidative stress biomarker at pulmonary tuberculosis in Semarang city, Indonesia. Southeast Asian Juornal of Tropical medicine and publich health SEAMEO TROPMED, Accepted 2013

CLONING AND IN VITRO ANTI-MYCOBACTERIAL ACTIVITY OF LECTIN PROTEIN IN COMBINATION WITH STREPTOMYCIN TO INCREASE SENSITIVITY AGAINST Mycobacterium tuberculosis International Journal of Biotechnology and Biochemistry.

ISSN 0973-2691 Volume 8, Number 2 (2012) pp. 101-117

Inhibitive enhancement of Isoniasid treatment on Mycobacterium tuberculosis through steroid and triterpenoid carboxilic acid from red algae euchema spinosum International Journal of Pharma and Bio Sciences (IJPBS), INDIA. Accepted 2013

Sasmono RT, Massi MN, Setianingsih TY, Wahyuni S; Anita, Halik H, Yusuf I, Dick T, Sola C, Bifani PJ, Phyu S. Heterogeneity of Mycobacterium tuberculosis strains in Makassar, Indonesia. Int J Tuberc Lung Dis. 2012 Nov;16(11):1441-8.

Massi MN, Wahyuni S, Halik H; Anita, Yusuf I, Leong FJ, Dick T, Phyu S. Drug resistance among tuberculosis patients attending diagnostic and treatment centres in Makassar, Indonesia. Int J Tuberc Lung Dis. 2011 Apr;15(4):489-95.

Identification and sequencing of isolates of Salmonella enterica serotype typhi obtained from patients with perforation and non-perforation typhoid fever. South east asian Journal of tropical Medicine and public Health. Vol. 3 No. 1 118-122. January; 2005.

Presence of a mutation in ponA1 of Neisseria gonorrhoeae in numerous clinical samples resistant to various1. beta-lactams and other, structurally unrelated, antimicrobials. J Infect Chemother. 2005 Oct;11(5):226-30

Polymorphism of the interleukin-4, interleukin-13, and signal transducer and activator of transcription 6 genes in Indonesian children with minimal change nephrotic syndrome. Am J Nephrol. 2005 Jan-Feb;25(1):30-5. Epub 2005 Feb 1

SCCmec typing and detection of VISA-related genes in methicillin-resistant Staphylococcus aureus clinical strains from Kobe University Hospital, Japan. Southeast Asian J Trop Med Public Health. 2006 Nov;37(6):1149-55.

The comparison mycobacterium leprae particle agglutination (MLPA) test between leprosy and normal individual. Majalah Kedokteran Bandung, Indonesia. April 31; 1999; Vol 3.. 161-166

Identification of IgM antibody by MLPA test and Relationship with DNA M leprae from housedust in leprosy endemic area. Journal Medica Nusantara. Indonesia. April-June 2001; Vol. 22 No.2.319-323.

The Seroprevalence of IgM anti Phenolic Glycolipid‑I (PGL‑I) antibody in medical students of Hasanuddin University. YARSI Medical J. Vol.7, no. 2, hal 1‑8 (1999).

Detection of DNA Salmonella typhi using nested PCR from blood filter paper of typhoid fever University. Proceeding 13th Indonesian Scientific Conference in Japan (2004).

The applicability of nested PCR for detection DNA Salmonella typhi in the urine of patients with suspected typhoid fever. Ebers Papyrus Medical J. (2005).

Detection of DNA Mycobacterium leprae from housedust in leprosy endemic area in south sulawesi Indonesia by PCR. Proceeding 13th Indonesian Scientific Conference in Japan , 2004

DNA polimerase chain reaction test on Mycobacterium tuberculosis from sputum of individuals with contact to tuberculosis BTA positive patients in Makassar, Jurnal Medika Nusantara, vol 28, no 3 , 2007

BIOGRAPHICAL SKETCH

NAME Gemini Alam, M.Sc., Ph.D., Prof.		POSITION Investigator of anti TB extraction and isolation
EMAIL daengta007@yahoo.com
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.)
INSTITUTION AND LOCATION	DEGREE (if applicable)		MM/YY	FIELD OF STUDY
Hasanuddin University, Makassar, Indonesia	BSc		1983 – 1989	Pharmacy
Gadjah Mada University, Makassar, Indonesia	MSc		1993 – 1996	Pharmacy Biology
Gadjah Mada University, Yogyakarta, Indonesia	PhD		1999 – 2005	Pharmacochemistry

Positions & Honors

Positions

1999-present Journal of Traditional Medicine, Editor

1999-present Journal of Natural Medicines, Editor

1990-present Pharmacy Faculty, Hasanuddin University, Lecturer

Honors

Basic Research, DIKTI, Hasanuddin University, 1996

Young Lecturer Research, DIKTI, Hasanuddin University, 1998

National Competitive research, DIKTI, 2003 – 2005

Marine Science, Research and Technology Ministry, 2002-2003

I-MHERE Research Project, WHO, 2006 – 2007

National Strategic Research, DIKTI, 2008 – 2009

National Strategic Research, DIKTI, 2012 – 2013

BOPTN – Innovation Research, 2014

Publications

Alam, G., 2000, Antihistaminic Compounds Isolated from Vitextrifolia L., LACDR – Natural Product Seminar, Department of Pharmacognosy, Leiden University, The Netherlands, 2 March 2000

Alam, G., Wahyuono, S., Ganjar, I.G., Hakim, L., Timmerman, H., 2000, Antiasthmatic Indonesian Medicinal Plants: Their Tracheospasmolytic Activity Induced by Histamine, International Sendai Histamine Symposium, November 22-25, 2000, Sendai, Japan

Alam, G., Wahyuono, L., Hakim, L., Ganjar, I.G., 2001, Efekpenghambatandanpemicukontraksitrakeadariekstrak n-heksandaunEugenia caryophyllata THUNB, MajalahObatTradisional, Vol. 6, No.18,16-24.

Alam, G., Wahyuono, S., Ganjar, I.G., Hakim L., Timmerman, H., Verpoorte, R., 2002, Tracheospasmolytic Activity of Viteosin-A and Vitexicarpin Isolated from the Leaves of Vitextrifolia L., PlantaMedica, 68, p. 1047-49

Ilham, Alam, G., Tobo, F., 2002, Pharmacological Effects of Methanol Extract of Kayusanrego (LunasiaamaraBlanco) leaves on Mice, The Journal of Traditional Medicines, Vol. 7, No. 20, 13-18.

Alam, G., Sudarmanto, B.S.A., Astuti, P., Wahyuono, 2002, PemodelanmolekulsenyawaViteosin-A, SenyawaaktifTrakeospasmolitikdaridaunVitextrifolia, MajalahFarmasi Indonesia, Vol. 13(4), 180-184

Astuti, P.,Alam, G., Tahir, A., Wahyuono, S., 2002, Brine Shrimp Letallity Test of Marine SongeJaspissp Fractions, Farmakon, 3 (1), 17-21.

Astuti, P., Alam, G., Tahir, A., Wahyuono, S., 2002, Screening Toxicity of Marine Sponges Collected from BarrangLompoIsland against Larva ArtemiasalinaLeach, The Journal of Traditional Medicines, Vol 7. No.21, 19-23

Alam, G., 2002, SenyawaantialergidariTanamanObat Indonesia, Journal of Traditional Medicines, Vol 7. No.22, 32-7

Astuti, P., Alam, G., Tahir, A., Wahyuono, S., 2002, SponLautJaspissp, SumberAlamAktifBerpotentialsebagai Anti Kanker, BerkalaIlmiahKedokteran,

Gandjar, I.G., Alam, G., Wahyuono, S., 2002, “Jamu Antiasthma”, Indonesian Traditional Preparations as The Start of Antiasthmatic Drug Discovery, Pharmacy Scientific Conference 2002, “New Challenges in Pharmacy Practice”, Penang Malaysia, 31 October – 2 November 2002

Astuti, P., Alam, G., Wahyuono, S., 2003, Bioactivity Screening of Sponges Collected from Bunaken, Menado By Brine Shrimp Lethallity Test AgainstArtemiasalina Leach, Indonesian Journal of Pharmacy, 14(1), 238-243.

Astuti, P., Utami, S.T., Hertiani, T., Alam, G., Ahyadi, H., Wahyuono, S., 2003, Antibacterial screening of sponges extracts collected from Bunaken, Biota, Vol. III, No. 2.

Alam, G., Sari, D., Astuti, P., 2003, Fractionation and Toxicity Testing of Aceton Extract of Petrosiasp Originated from Bunaken Bay againstArtemiasalina Leach, Journal of Traditional Medicines, Vol.8. No.25, p. 20-24.

Alam, G., and Tayeb, R., 2003, Fractionation and Brine shrimp lethallity test of sea star methanol extract, Farmakon, In press

Alam, G., Adnan, A., Mahmud, AI, Djide, M.N., 2003, TLC Bioautography of antibacterial compounds from marine sponges ofCallyspongia sp., Journal of Traditional Medicines, Vol.8 No.23, 1-4

Alam G., 2004, Pharmacognosy study of VitextrifoliaL., Journal of Traditional Medicines, Vol.

Alam, G.,Wahyuono S., Gandjar, I.G., Hakim L., Ikawati, Z., Timmerman, H., Verpoorte, R., 2005, Potential anti-asthmatic compounds isolated from the leaves of VitextrifoliaL., KongresNasionalPerhimpunanAlergiImunologi Indonesia, 24-26 Maret,Yogyakarta

Alam G., Astuti P, Sari D.,Wahyuono S., Hamman MT., 2005, Structure Elucidation Of Bioactive Alkaloid Compounds Isolated From Sponge PetrosiaSp Collected From Bunaken Bay Menado, Indonesian Journal of Chemistry

Alam G., Wahyuono S., Gandjar, I.G., Hakim L., Timmerman, H., Verpoorte R., 2005, Tracheospasmolytic activity of Vitetrifolin-E isolated from Vitextrifolia L., Phytotherapi Research,

Astuti, P., Alam., G., Wahyuningsih, M.S.H., Sari., D., Wahyuono., 2005, Characterization of Bioactive Compounds Isolated from Petrosiasp: Its Potency for The Development of Anticancer Drugs, Jurnal Gama Sains

Alam G., (Invited Lecture), 2006, Potential antiasthma of VitextrifoliaL. leaves, International symposium of Asean Medicinal Plant – ASOMPS, Padang, West Sumatera, Indonesia, November 2006

Nugroho, A.E., Alam., G., 2006, EfekfarmakologitanamanobatLegundi (Vitextrifolia L), MajalahObatTradisional, Vol, 11, No.39, hal 25-30

Alam G., (Invited speakers), 2007, SehatdanCantikdenganbahanalami, Talk show dalam Launching BRI UntungBeliung, UlangTahun BRI Sulsel, Pinrang 5 Maret 2007.

Alam G., (Invited speakers) 2007, Tracheospasmolytic activity of infusion of legundi (VitextrifoliaL), International Joint Symposium of Indonesian traditional medicine – IOCD, Surabaya, 9-11 maret 2007

Alam G., Wahyuono S., Gandjar, I.G., Hakim L., Timmerman, H., Verpoorte R., 2007, Viteksikarpin Flavonoid, PotensialAntiasmadariekstrakdaunLegundi (Vitextrifolia), Seminar NasionaldanKongresIlmiah ISFI, Jakarta, 18-19 Juni 2007

Alam G.,Wahyuono S., Gandjar, I.G., Hakim L., Timmerman, H., Verpoorte R., 2007, Toxicity acute of standardized ethanolic extract of legundi (VitextrifoliaL), International Symposium of Indonesian herbal medicine, UBAYA – UNAIR – PERHIPBA, Surabaya, 6-8 September 2007

Alam G., 2007, (Invited speakers), PenemuanObatAntiasmadaribahanobatalam Indonesia, Seminar Nasional “Drug discovery”, Launching FakultasFarmasi UNHAS, 13 November 2007

Alam., G., 2014, Antiasthmatic agents from Indoensian Natural Medicines, Visiting speakers at The Campus Asia Project, Institute of Natural Medicines, Toyama University, Japan.

BIOGRAPHICAL SKETCH

NAME Herlina Rante, M.Sc., Ph.D.		POSITION Investigator of anti malaria in vitro assay
EMAIL h_rante@yahoo.co.id
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.)
INSTITUTION AND LOCATION	DEGREE (if applicable)		MM/YY	FIELD OF STUDY
Hasanuddin University, Makassar, Indonesia	BSc		1997 – 2002	Pharmacy
Hasanuddin University, Makassar, Indonesia	MSc		2002 – 2005	Pharmacy
Gadjah Mada University, Yogyakarta, Indonesia	PhD		2007 – 2012	Pharmacy Biology

Positions

2002-present Pharmacy Faculty, Hasanuddin University, Lecturer

Publications

Journal Articles

Rante, H., Ali, A., Microbes Based Technology Applications in Food Sources search efforts. Bionature Journal, Vol. No. 6. 1, April 2005, p: 40-46.

Rante, H., Ali, A., Toxicity Test of Mangrove Snail Meat Extract Against Artemia Salina Leach, Journal of Pharmacy and Pharmacology, Vol. No. 10. 1, March 2006, p: 6-11.

Rante, H., Wahyono, Alam,G., Murti,YB., Antibacteria Activity test from Actinomycetes sponge symbiont and profile active compounds in TLC -Bioautografi. Proceedings of the National Seminar Eight Star Performance Pharmacist, PPS Fak. Pharmacy Gadjah Mada University (UGM), December 27, 2010.

Rante,H., Wahyono., Gene Sequence Analysis of Non-Ribosomal Peptide synthetase In Actinomycetes Associated Sponge toward Structure Compounds of Multidrug resistances Bacteria. National Seminar on Natural Products for Infectious Disease Control, Graduate Pharmaceutical Sciences UGM and C-Nair Fak. Pharmacy UGM, 2011

Rante, H., Wahyono, Alam, G., Murti, YB., Isolation and Characterization of Actinomycetes Associated Spons which produce antibacterial activity. The International Conference on Drug Development from Natural Resources, Fak. Farmasi Universitas Ahmad Dahlan, Yogyakarta, June 30 2012

Rante, H., Wahyono, Alam, G., Murti, YB., Isolation and Characterization of Actinomycetes Sponges Associated producing of antibiotic Collected from Barrang Lompo Island, Makassar. Wallace Darwin Science Symposium, Hasanuddin University Makassar, 4-5 September 2012.

Rante, H., Ali, A., Thamrin,S., The development of formula based on tropicals actinomycetes to prevent of pepper stem rot diseases ( A case of attack stem rot disease of pepper by Phytophthora capsici ) International Spices Conference, Revitalization of Spice Quality and Production in the Perspective of Sustainability and Environmental Responsibility, Ambon 19-21 Agustus 2013

Rante,H., Wahyono, Alam, G., Murti, Y.B., Purification and Characterization of Anti-multidrug resistances Bacteria from Actinomycetes Associated Sponge, Indonesian Pharmaceutical Journal , vol. No. 21. 3, 2010

Mufidah, Rante,H., Rahim,A., Agustina, R., Pakki,E., Talbani,A., Antifungi Activity of Secondary Metabolite Endophytic Fungi which Isolation from Mezzetia parviflora, Majalah Farmasi dan Farmakologi, Vol.17, No.3, 2013

wahyuni

Sitti Wahyuni, MD. PhD.

Epidemiology of Topical Disease Project Leader

Senior Lecturer in Parasitology and Immunology

Biography

After graduated from Hasanuddin University Medical Faculty and finished her duty work at primary health centre, Pusat Kesehatan Masyarakat, Bantimurung, Kabupaten Maros in 1996, Sitti Wahyuni began her carrier as a university lecturer in Faculty of Medicine, Hasanuddin University and was appointed in the Department of Parasitologi. Following year until 2000 she conducted several epidemiology studies in the field of parasitology. In April 2001 she began her doctoral studies as assistant-in-opleiding (AIO) at the Department of Parasitology, Leiden University, the Netherlands to study the relationship between helminth infection and allergy. From 2006-2014 she is working as researcher in Novartis-Eijkman-Hasanuddin Clinical Research Initiative (NEHCRI/NHCR) where she concentrates to study the epidemiology of Tuberculosis and Dengue infections. In 2013, Wahyuni was appointed as coordinator of Hasanuddin University Medical Research.

Alongside regular curricular teaching, Sitti Wahyuni has placed much emphasis into training biomedical and medical undergraduate and candidate of master and doctoral students, not only from Hasanuddin University but also from institutions that affiliated or collaborated with Hasanuddin University

Research interest

Sitti Wahyuni is interested in studying epidemiology-immunology of tropical diseases and the modulation of Helminth, Malaria, Mycobacterium, Dengue and Microbiome into immune system. She also interested to study molecule/protein in order to understand its role in pro- and anti-inflammatory status.

Peer-Reviewed Publications

Nurhayana Sennang, Stephen Rogerson, Sitti Wahyuni, Irawan Yusuf and Din Syafruddin. Antibody response against three Plasmodium falciparum merozoite antigens in Mamuju District, West Sulawesi Province, Indonesia. Malaria Journal 2014, 13:381 doi:10.1186/1475-2875-13-381. Published: 25 September 2014

Anna Albers, Erliyani Sartono, Sitti Wahyuni, Maria Yazdanbakhsh, Rick M. Maizels, Ute Klarmann-Schulz, Kenneth Pfarr, Achim Hoerauf.Real-time PCR Detection of the HhaI gene in pre- and post-patent Brugia malayi Infections: a Study in Indonesian Transmigrant. Parasit Vectors. 2014 Mar 31;7:146. doi: 10.1186/1756-3305-7-146

Firdaus Hamid, Aprilianto E. Wiria, Linda J. Wammes, Maria M. M. Kaisar, Yenny Djuardi, Serge A. Versteeg, Sitti Wahyuni, Ronald van Ree, Erliyani Sartono, Taniawati Supali, and Maria Yazdanbakhsh. Risk Factors Associated with the Development of Atopic Sensitization in Indonesia. PLoS One. 2013 Jun 19;8(6):e67064.

Aprilianto E. Wiria, Firdaus Hamid, Linda J. Wammes, Maria M. M. Kaisar,² Linda May, Margaretta A. Prasetyani, Sitti Wahyuni, Yenny Djuardi,² Iwan Ariawan, Heri Wibowo, Bertrand Lell, Robert Sauerwein, Gary T. Brice, Inge Sutanto, Lisette van Lieshout, Anton J. M. de Craen, Ronald van Ree, Jaco J. Verweij, Roula Tsonaka, Jeanine J. Houwing-Duistermaat, Adrian J. F. Luty, Erliyani Sartono,² Taniawati Supali, and Maria Yazdanbakhsh.The effect of three-monthly albendazole treatment on malarial parasitemia and allergy: a household-based cluster-randomized, double-blind, placebo-controlled trial. PLoS One. 2013;8(3):e57899. doi: 10.1371/journal.pone.0057899. Epub 2013 Mar 19.

Hamid F, Wiria AE, Wammes LJ, Kaisar MM, Lell B, Ariawan I, Uh HW, Wibowo H, Djuardi Y, Wahyuni S, Schot R, Verweij JJ, van Ree R, May L, Sartono E, Yazdanbakhsh M, Supali T. A longitudinal study of allergy and intestinal helminth infections in semi urban and rural areas of Flores, Indonesia (ImmunoSPIN Study). BMC Infect Dis. 2011 Apr 1;11:83.

Wiria AE, Prasetyani MA, Hamid F, Wammes LJ, Lell B, Ariawan I, Uh HW, Wibowo H, Djuardi Y, Wahyuni S, Sutanto I, May L, Luty AJ, Verweij JJ, Sartono E, Yazdanbakhsh M, Supali T. Does treatment of intestinal helminth infections influence malaria? Background and methodology of a longitudinal study of clinical, parasitological and immunological parameters in Nangapanda, Flores, Indonesia (ImmunoSPIN Study). BMC Infect Dis. 2010 Mar 25;10:77.

van Riet E, Wuhrer M, Wahyuni S, Retra K, Deelder AM, Tielens AG, van der Kleij D, Yazdanbakhsh M. Antibody responses to Ascaris-derived proteins and glycolipids: the role of phosphorylcholine. Parasite Immunol. 2006 Aug;28(8):363-71.

Yazdanbakhsh M, Wahyuni S. The role of helminth infections in protection from atopic disorders. Curr Opin Allergy Clin Immunol. 2005 Oct;5(5):386-91.

Wahyuni S, Sartono E, Supali T, van der Zee JS, Mangali A, van Ree R, Houwing-Duistermaat JJ, Yazdanbakhsh M. Clustering of allergic outcomes within families and households in areas endemic for helminth infections. Int Arch Allergy Immunol. 2005 Apr;136(4):356-64. Epub 2005 Mar 2.

Noordin R, Wahyuni S, Mangali A, Huat LB, Yazdanbakhsh M, Sartono E. Comparison of IgG4 assays using whole parasite extract and BmR1 recombinant antigen in determining antibody prevalence in brugian filariasis. Filaria J. 2004 Aug 12;3(1):8.

Wahyuni S, Houwing-Duistermaat JJ, Syafruddin, Supali T, Yazdanbakhsh M, Sartono E. Clustering of filarial infection in an age-graded study: genetic, household and environmental influences. Parasitology. 2004 Mar;128(Pt 3):315-21.

Wahyuni S, Van Ree R, Mangali A, Supali T, Yazdanbakhsh M, Sartono E. Comparison of an enzyme linked immunosorbent assay (ELISA) and a radioallergosorbent test (RAST) for detection of IgE antibodies to Brugia malayi. Parasite Immunol. 2003 Nov-Dec;25(11-12):609-14.

Terhell AJ, Wahyuni S, Pryce A, Koot JW, Abadi K, Yazdanbakhsh M. Anti-filarial and total IgG4 and IgE antibody levels are correlated in mothers and their offspring. Trans R Soc Trop Med Hyg. 2002 May-Jun;96(3):334-9.

BIOGRAPHICAL SKETCH

NAME Subehan, M.Pharm.Sc.,, Ph.D.		POSITION Investigator of anti malaria antigen extraction and isolation
EMAIL Sube_han@yahoo.com
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.)
INSTITUTION AND LOCATION	DEGREE (if applicable)		MM/YY	FIELD OF STUDY
Hasanuddin University, Makassar, Indonesia	BSc		1994 – 1999	Pharmacy
Toyama University, Japan	MPharmSc		2003 – 2005	Natural Medicine
Toyama University, Japan	PhD		2005 – 2008	Natural Medicine
Toyama University, Japan	Diploma		11/09	Drug Discovery
Toyama University, Japan	Diploma		04/10	Natural Medicine

Positions

2001-present Pharmacy Faculty, Hasanuddin University, Lecturer

Publications

Subehan, Tepy Usia, Shigetoshi Kadota and Yasuhiro Tezuka. Constituents of Zingiber aromaticum and Their CYP3A4 and CYP2D6 Inhibitory Activities. Chemical and Pharmaceutical Bulletin, March 2005, 53(3), 333―335. (Note)

Jun Yin, Yasuhiro Tezuka, Subehan, Liying Shi, Jun-ya Ueda, Katsumichi Matsushige, and Shigetoshi Kadota. Combination of Soft-Shell Turtle Powder and Essential Oil of a Unicellular Chorophyte Prevents Bone Loss and Decreased Bone Strength in Ovariectomized Rats.Biological and Pharmaceutical Bulletin, February 2005, 82(2), 275―279. (Full Article)

Subehan, Jun-ya Ueda, hiroharu Fujino, faisal Attamimi and Shigetoshi Kadota. A field survey of agarwood in Indonesia. Journal of Traditional Medicine, September 2005, 22(4), 244―251. (News Letter)

Jun Yin, Yasuhiro Tezuka, Subehan, Liying Shi, Jun-ya Ueda, Katsumichi Matsushige, and Shigetoshi Kadota. In vitro anti-osteoporotic of isotaxiresinol, a lignan from wood of Taxus yunanensis. Phytomedicine, February 2006, 13, 37―42. (Full Article)

Subehan, Tepy Usia, Shigetoshi Kadota and Yasuhiro Tezuka. Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian Medicinal Plants.Journal of Ethnopharmacology. May 2006, 105 (3), 449―455. (Full Article)

Subehan, Tepy Usia, Shigetoshi Kadota and Yasuhiro Tezuka. Mechanism-based inhibition of Human Liver Microsomal Cytochrome P450 (CYP2D6) by Alkamides of Piper nigrum L. Planta Medica, May 2006, 72(6), 527―532. (Full Article)

Subehan, Tepy Usia, Shigetoshi Kadota and Yasuhiro Tezuka. Alkamides from Piper nigrum L and their inhibitory activity against human liver microsomal Cytochrome P450 (CYP2D6).Natural Product Communications. 2006, 1(1), 1―7. (Full Article)

Liying Shi, Yasuhiro Tezuka, Subehan, Jun-ya Ueda, Tatsuro Miyahara, Jun Yin, Takahiro Nobukawa, and Shigetoshi Kadota. Inhibitory effect of Kampo medicines on bone reseption in vitro and preventive effect on bone loss in vivo. Journal of Traditional medicines 06, 23(3), 92―100. (Full Article)

Aty Widyawaruyanti, Subehan, Surya Kant Kalauni, Suresh Awale, Maria Nindate, Noor Cholies Zaini, Din Syafruddin, Puji Budi Setia Asih, Yasuhiro Tezuka, Shigetoshi Kadota. New prenylated flavones from Artocarpus champeden and their antimalarial activity in vitro. Journal of Natural Medicines 2007, 61(4), 410―413. (Note)

Mangestuti, Subehan, Aty Widyawaruyanti, Syed Faisal Haider Zaidi, Suresh Awale, Shigetoshi Kadota. Traditional Medicine of Madura Island in Indonesia.Journal of Traditional Medicine 2007, 24(3), 90―103. (News Letter)

Subehan, Syed Faisal Haider Zaidi, Shigetoshi Kadota and Yasuhiro Tezuka. Inhibition on human liver cytochrome P450 3A4 by constituents of Fennel (Foeniculum vulgare): Identification and characterization of a mechanism-based inactivator. JournalAgricultural and Food Chemistry 2007, 55(6), 10162―10167. (Full article)

Naoki Toyooka, Dejun Zhou, Soushi Kobayashi, Hiroshi Tsuneki, Tsutomu Wada, Hideki Sakai, Hideo Nemoto, Toshiyasu Sasaoka,Yasuhiro Tezuka, Subehan, Shigetoshi Kadota, H. Martin Garraffo, Thomas S. Spande, John W. Daly. Syntheses of the proposed structures of poison-frog alkaloids 179 and 207E and their inhibitory effects on neuronal nicotinic Acethylcholine receptors. Synlett 2008, 2008 (1), 61―64. (Letter)

Subehan, Shigetoshi Kadota and Yasuhiro Tezuka. In vitro Inhibition on human liver cytochrome P450 3A4 by a new constituent isolated from Cinnamomum burmani. Planta Medica 2008, 74. 1474―1480. (Full article)

Subehan, Naoto Takahashi, Shigetoshi Kadota and Yasuhiro Tezuka. Cytochrome P450 2D6 inhibitory constituents of Lunasia amara. Phytochemistry Letters 2010 (Accepted) on line 5 november 2010. http://www.sciencedirect.com/science?_ob=ArticleListURL&_method=list&_ArticleListID=1589574511&_sort=r&_st=13&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=eac8ab3b89acb20b4403f6adf4d47b12&searchtype=a

BIOGRAPHICAL SKETCH

NAME Yulia Yusrini Djabir, M.Biomed.Sc., M.Sc., Ph.D.		POSITION Investigator of anti Malaria drug compound screening
EMAIL yuliayusrini@yahoo.com
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.)
INSTITUTION AND LOCATION	DEGREE (if applicable)		MM/YY	FIELD OF STUDY
Hasanuddin University, Makassar, Indonesia	BSc		1996 -2001	Pharmacy
Hasanuddin University, Makassar, Indonesia	MSc		2002 – 2007	Pharmacy
James Cook University, Australia	MBiomedSc		2006 – 2008	Biomedical Science
James Cook University, Australia	PhD		2010 – 2014	Biomedical Science

Positions

2002-present Pharmacy Faculty, Hasanuddin University, Lecturer

Publications

Cardiac stability and hemodynamicrecovery with adenosine-lidocaine/Mg2+ (ALM) compared to standardof care epinephrinefollowingasphyxial cardiac arrest duringhypothermia and rewarming, 2013, HBPRCA AnnualScientific MeetingMelbourne

Adenosine, Lidocaine, and Mg2⁺(ALM) increases survival andcorrects coagulopathy after eightminuteasphyxial cardiac arrest inthe rat, 2013,SHOCK , Vol. 40, No. 3,pp.222-232

Hemodynamic Rescue andElectrocardiogram Stability DuringChest Compressions UsingAdenosine andLidocaine (AL) After8-Min Asphyxial Hypoxia In The Rat, 2013, American Journal ofEmergency Medicine,Vol 31, Issue 11, pp.1539-1545

Cardiac Rescue and stabilizationwith a small intravenous (i.v) bolusof adenocaine following 8 minasphyxial hypoxia in the rat in vivo:Effect of Therapeutic Hypothermia, 2011, American HeartAssociation ScientificSession, Dallas, USA